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Studies:
[1] Studies on the ingredient Capsicum annuum/Capsaicinoids:
Health Claims by EFSA (Status: pending):
Capsicum annuum contributes to weight reduction.
Capsicum annuum supports weight loss programs.
a) Lipids Health Dis. 2010; 9: 72. Published online 2010 Jul 15. doi: 10.1186/1476-511X-9-72 PMCID: PMC2912905 PMID: 20633266. Effect of oral intake of capsaicinoid beadlets on catecholamine secretion and blood markers of lipolysis in healthy adults. Richard J. Bloomer, Robert E. Canale, Sid Shastri, Sujata Suvarnapathki.
b) Effects of red pepper added to high-fat and high-carbohydrate meals on energy metabolism and substrate utilization in Japanese women. Yoshioka M, et al. Br J Nutr 1998;80: 503–510.
c) doi: 10.1016/j.appet.2017.02.025. Epub 2017 Feb 21. Effects of twelve weeks of capsaicinoid supplementation on body composition, appetite and self-reported caloric intake in overweight individuals.
Stacie L Urbina, Michael D Roberts, Wesley C Kephart, Katelyn B Villa, Emily N Santos, Alyssa M Olivencia, Haley M Bennett, Marissa D Lara, Cliffa A Foster, Martin Purpura, Ralf Jäger, Lem W Taylor, Colin D Wilborn.
d) Capsaicinoids Enhance Metabolic Rate in Normal Healthy Individuals using a Novel Metabolic Tracker Breezing Device – An Open Label Placebo Controlled Acute Study
Yue Deng, Fang Chen, Erica Forzani, Vijaya Juturu.
Center of Bioelectronics and Biosensors, Bio-design Institute, Arizona State University, Arizona, USA.
OmniActive Health Technologies Inc, Morristown, New Jersey, USA.
e)https://academic.oup.com/cdn/article/5/Supplement_2/514/6293652https://academic.oup.com/cdn/article/5/Supplement_2/514/6293652
https://academic.oup.com/cdn/article/5/Supplement_2/514/6293652
https://academic.oup.com/cdn/article/5/Supplement_2/514/6293652
[2] Studies on the ingredient Glucomannan:
a) Au-Yeung F, et al. The effects of gelled konjac glucomannan fiber on appetite and energy intake in healthy individuals: a randomized cross-over trial. Br J Nutr. 2018; 119(1):109-116.
b) Bonetti G, et al. Dietary supplements for obesity. J Prev Med Hyg. 2022; 63(2 Suppl 3): E160–E168.
c) Devi Devaraj R, et al. Health-promoting effects of konjac glucomannan and its practical applications: A critical review. Int J Biol Macromol. 2019; 126: 273-281.
d) EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the substantiation of health claims related to konjac mannan (glucomannan). EFSA Journal 2010; 8(10): 1798.
e) Fang Y, et al. Konjac Glucomannan: An Emerging Specialty Medical Food to Aid in the Treatment of Type 2 Diabetes Mellitus. Foods. 2023;12(2):363.
f) Moraru C, et al. A Meta-Analysis on Randomized Controlled Clinical Trials Evaluating the Effect of the Dietary Supplement Chitosan on Weight Loss, Lipid Parameters and Blood Pressure. Medicina (Kaunas). 2018; 54(6): 109.
g) Zhang Z, et al. Effects of Glucomannan Supplementation on Type II Diabetes Mellitus in Humans: A Meta-Analysis. Nutrients. 2023; 15(3): 601.
[3] Studies on the ingredient Green Tea Extract:
a) Hursel, R., Viechtbauer, W. & Westerterp-Plantenga, M. (2009): The effects of green tea on weight loss and weight maintenance: a meta-analysis. Int J Obes 33, 956–961.
b) Rothenberg, D. O., et al. (2018): A Review on the Weight-Loss Effects of Oxidized Tea Polyphenols. Molecules (Basel, Switzerland), 23(5), 1176. https://doi.org/10.3390/molecules23051176https://doi.org/10.3390/molecules23051176https://doi.org/10.3390/molecules23051176
https://doi.org/10.3390/molecules23051176
https://doi.org/10.3390/molecules23051176
[4] Studies on the ingredient Beta Glucans:
a) Howard, E. J., Meyer, R. K., Weninger, S. N. et al. (2024). Impact of Plant-Based Dietary Fibers on Metabolic Homeostasis in High-Fat Diet Mice via Alterations in the Gut Microbiota and Metabolites. The Journal of Nutrition.
b) University of Arizona. How your morning oats could help you manage your weight.
[5] Studies on the ingredient Choline:
a) https://pubmed.ncbi.nlm.nih.gov/27341028/
b) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570899/
c) https://www.ncbi.nlm.nih.gov/pubmed/4340541
d) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863971/
e) https://www.efsa.europa.eu/en/efsajournal/pub/4484
f) https://pubmed.ncbi.nlm.nih.gov/36432547/https://pubmed.ncbi.nlm.nih.gov/36432547/
